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Comprehensive care for your overall wellness.

You deserve a healthy, beautiful smile - the team at Preston Dental Center provides personalized care solutions to help you get the smile you've always wanted.

We’re proud to serve Cary and our local community. Come visit us at 3761 NW Cary Pkwy, Ste 100.

Why Choose Preston Dental Center:

  1. We're experienced

    We provide life-enhancing dental care solutions in our community. Patients choose us for our proven reputation, expertise, and commitment to using the most up to date techniques and technology.

  2. We put patients first

    Oral health care is a partnership. We take the time to get to know our patients, understand their needs and goals, and create treatment plans tailored to their lifestyles.

  3. We provide comprehensive care

    Our skilled team is trained to not only treat patients but also to identify the root of the cause of symptoms so we can help you get your healthiest smile ever and set you up for great long-term oral health.

  4. We are dependable

    Our compassionate team is dedicated to delivering the highest standard of care and will ensure you feel comfortable and confident about your care each step of the way.

Joseph G. Mayes, DDS


Joseph G. Mayes, DDS

Dr. Mayes has significant postgraduate education in cosmetic dentistry, dental crowns, bridges, veneers, and tooth-colored restoration using modern composite materials. He also has completed a dental sleep medicine mini-residency at UNC-Chapel Hill School of Dentistry and is a member of the American Academy of Dental Sleep Medicine. Away from the office, Dr. Mayes is happily married to Dr. Lisa.

Isaac J. Edwards, DDS


Isaac J. Edwards, DDS

Born and raised in Cary, Dr. Ike Edwards was a patient of the practice long before he joined the team. As an undergraduate student, he shadowed Drs. Greg and Lisa Mayes and then worked alongside them as a dental assistant before going to dental school. Outside the office, he enjoys cooking, exercising, traveling, trying new restaurants, and visiting his family farm.

"Smiles change lives. It's time to let yours shine."


Quality, comfortable care.

Whether you need preventative care or want to correct your smile with cosmetic dentistry services, we are here to help you achieve your smile goals.


Everything you need for a healthy smile.

See all the dental services we can provide for you.

Explore Our Services